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Under-Eye Polynucleotides

A next generation skin treatment

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All about
Polynucleotides

A newer generation of regenerative therapy, polynucleotides work on a cellular level to repair and rejuvenate delicate under-eye tissue. They help to reduce puffiness, improve firmness, and brighten the overall appearance of the eye area over time by stimulating collagen and elastin production.

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Polynucleotides are one of the most advanced regenerative options for rejuvenating the delicate under-eye area. Rather than adding volume, they work on a deep cellular level to repair, hydrate, and strengthen the skin from within. Derived from purified DNA fragments, these naturally bio-compatible molecules trigger fibroblast activity—the cells responsible for producing collagen, elastin, and hyaluronic acid—helping to restore firmness, smooth fine lines, and reduce crepiness or dullness. This treatment is ideal for clients experiencing early signs of ageing such as fine lines, loss of elasticity, dark shadows, or mild hollowness under the eyes. It’s also perfect for those who feel tired even when well-rested, or who want to improve skin quality without traditional fillers. Because polynucleotides are regenerative rather than volumising, they’re a beautiful choice for anyone seeking subtle, natural rejuvenation and long-term skin health. A typical course includes 2–3 sessions spaced about 2–4 weeks apart, depending on individual skin needs. Most clients begin to notice visible improvements in skin texture and brightness within 3–4 weeks, with results continuing to develop over the following months as collagen and elastin production increases. Maintenance top-ups every 6–9 months help to keep the results consistent and the skin in its optimal condition. The procedure itself is quick—usually around 20–30 minutes—and involves a series of tiny, precise injections to deliver the polynucleotides directly into the under-eye tissue. There’s minimal downtime, though mild redness or swelling may appear for a few hours post-treatment. Over time, the skin becomes smoother, firmer, and more luminous, with a fresher, well-rested appearance that looks completely natural. Polynucleotides are a beautiful choice for those who value regenerative, science-led treatments that enhance skin quality rather than alter facial structure—helping you look like the best version of yourself, rested and radiant from within.

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A personal note....

I’ve fallen in love with polynucleotides because they represent everything I value in aesthetics—science, subtlety, and true skin healing. Over the years, I’ve seen so many clients who want to rejuvenate their skin but are hesitant about looking “done.” Polynucleotides are the perfect answer. They don’t alter your natural features; they simply help your skin remember how to function optimally again. For me, this treatment bridges the gap between clinical precision and holistic rejuvenation—it’s regenerative beauty at its finest. Watching my clients’ skin transform week by week, becoming smoother, fresher, and more alive, is such a joy. It’s not just about looking better—it’s about helping your skin feel better from within. Danielle x

Alexa Young, CA

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