Polynucleotides are one of the most advanced and exciting innovations in regenerative aesthetics. Derived from purified DNA fragments, these biostimulating molecules work by repairing and rejuvenating the skin’s cellular structure. When injected, they trigger the body’s natural healing processes—stimulating fibroblast activity, boosting collagen and elastin production, improving tissue regeneration, and enhancing hydration deep within the skin. Unlike traditional dermal fillers that simply add volume, polynucleotides work on a deeper biological level to restore the skin’s quality and function over time. They improve elasticity, firmness, and luminosity while reducing fine lines, inflammation, and signs of fatigue. The result is a healthier, more youthful complexion that continues to improve in the weeks following treatment. Polynucleotides are suitable for both men and women looking for a subtle, natural enhancement. They’re particularly effective for those experiencing dullness, loss of elasticity, fine lines, under-eye crepiness, acne scarring, or sun damage. Treatments can be used alone or combined with other regenerative therapies such as PRF, skin boosters, or microneedling to further amplify results. Because they work with your body’s own repair mechanisms rather than masking imperfections, polynucleotides are ideal for anyone seeking a science-led, holistic approach to skin rejuvenation—one that enhances long-term skin health and radiance rather than temporary correction.